Your sister (to sleep) now?,They ( to run) now?,His mum (to

Is your sister sleeping now?

Are they running now?

Is his mum working now?

Are you brushing your teeth at the moment?

Is she washing her hands now?

Is it raining now?

Are pupils speaking now?

Is your brother running at the moment?

Is Tom feeding his dog now?

Is Kim making her bed now.

Пояснение: Слова now, at the moment указывают на Present Progressive Tense (истиннее долгое время), поэтому в общие вопросительные предложения нужно было воткнуть глагол be (формы am, is, are) в начало и добавить окончание -ing к главному глаголу.